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Anatomy of Heart

  • Large elastic arteries – Starts in Intima
  • Fat deposits, Hardening and destruction.
  • Major cause of IHD, MI & Stroke.
  • Incidence is decreasing since 1995
  • Better understanding & Change in life style.


  • Unknown etiology – Hyperlipidemia, life style, hypertension, smoking, genetic etc.
  • Starts with Initial intimal injury,  inflammation, necrosis, Lipid accumulation, Fibrosis –  Atheroma.
  • Leads to Obstruction or  destruction of vessel
  • Organ damage due to ischemia.
  • Complications – Thrombosis, embolism, aneurism, dissection & rupture.

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