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Oral Pathology

ORAL MANIFESTATIONS OF HIV

Ammatuna P., Campisi G., Giovanelli L., Giambelluca D., Alaimo C., Mancuso S. & Margiotta V. (2011). Presence of Epstein-Barr virus, cytomegalovirus and human papillomavirus in normal mucosa of HIV-infected and renal transplant patients. Oral Diseases, 7,1, (Jan), 34-40 Cattaneo C., Facchetti F., Re A., Borlenghi E., Majorana A., Bardellini E., …

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oral leukoplakia

To evaluate prevalence of Candidal carriage in Gingival crevicular fluid (GCF) taken from subgingival sites in individuals with oral leukoplakia. To evaluate prevalence of Candidal carriage in oral swabs taken from lesional site in subjects with oral leukoplakia.   To compare prevalence of Candidal carriage in GCF and oral swabs …

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opiod analgesics

Terminology History of Opioids Endogenous Opioid Peptides Opioid Receptors Structure of Opioids Binding of Opioids The Beckett-Casy Hypothesis Molecular Basis for Opioid Receptor Selectivity and Affinity Opioid Receptor Signaling and Consequent Intracellular Events Effects of Clinically Used Opioids Drugs It was not until the 1970’s that research allowed us to …

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OOO – AOT

At the end of the presentation learners should be able to explain the etiopathogenesis, clinical features, clinical and radiological differenrential diagnosis, histopathological features, investigations & treatment for Adenomatoid Odontogenic Tumour.     DENTIGEROUS CYST AMELOBLASTOMA MURAL AMELOBLASTOMA ADENOMATOID ODONTOGENIC TUMOUR MURAL ADENOMATOID ODONTOGENIC TUMOUR ODONTOGENIC KERATOCYST CENTRAL GIANT CELL GRANULOMA

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OMM-2011-III

Pink/Red color of lip -Blood is visible through thin parts of translucent epithelium No mucous glands  present. Like the skin, the transitional zone is exposed to atmosphere, but no glands present to keep it moist or preventing it from drying . So lips become dry easily and we lick our …

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OMM 2011-VI

The position of the gingiva on the surface of the tooth changes with time. When the tip of the enamel first emerges through the mucous membrane of the oral cavity, the epithelium covers almost the entire enamel. The tooth erupts until it reaches the plane of occlusion. The attachment epithelium …

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odontome OOO

Alteration or disturbances in the subsequent phases may also lead to odontoma formation. The complex odontomas arise due to defect in morphodifferentiation and histodifferentiation. Alteration in the mineralization mechanisms with modifications of the mineral component in the enamel may lead to incomplete maturation.   The complex odontomas may be caused …

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Odontoma

The term odontoma is used as a descriptor for any tumor of odontogenic origin. However, they have become known as mixed odontogenic tumors because they are composed of both epithelial and ectomesenchymal components.   As the complex odontoma, the compound odontoma is also of odontogenic origin. The pathogenesis of which …

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Odontogenic-Tumors

Projections of dental lamina into ectomesenchyme Layered cap (inner/outer enamel epithelium, stratum intermedium, stellate reticulum) Odontoblasts secrete dentin à ameloblasts (from IEE) à enamel Cementoblasts à cementum Fibroblasts à periodontal membrane   Developmental Lateral Periodontal Cyst [Slide 17 Content] From epithelial rests in periodontal ligament vs. primordial cyst – tooth …

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Odontogenic Tumors-IV

At  the end of the lecture student should be able to Describe etiology, Enlist clinical features, Enlist radiological features, Enlist histopathological features of Unicystic ameloblastoma & Calcifying epithelial odontogenic tumor   Growth of the ameloblastic epithelium into the connective tissue wall of the otherwise cystic neoplasm. The epithelium may remain …

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Odontogenic Tumors-III

At  the end of the lecture student should be able to Describe etiology, Enlist clinical features, Enlist radiological features, Enlist histopathological features of Squamous odontogenic tumor & Adenomatoid odontogenic tumor Lined by a single layer of cuboidal tcolumnar epithelial cells that have nuclei that frequently are polarized away from the …

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Odontogenic Tumors-Ib

Radiographically, the intraosseous ameloblastoma classically is described as a multilocular or ‘‘soap-bubble’’radiolucency. Other radiographic patterns seen are Smooth bordered unilocular radiolucency, A unilocular lucency with a scalloped or lobulated border, A poorly delineated mixed lucentopaque lesion The granular cells sometimes show a sharply delineated cell border, but most often the …

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Odontogenic Tumors-Ia

                                INTRODUCTION Odontogenic tumors are lesions derived from epithelial, ectomesenchymal  &/or mesenchymal elements that are or have been a part of tooth forming apparatus. Exclusively found in jaw bones (Intrabony or centrally located) or in the soft tissues overlying the tooth bearing areas (Peripherally located)   Benign odontogenic tumors …

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Odontogenic Tumors II

Proliferation of rests of Malassez in the PDL Primordial cyst of a supernumerary tooth germ Proliferation & cystic transformation of rests of dental lamina A Dentigerous cyst developing along the lateral aspect of crown   Cystic cavity is filled by keratin, usually in concentric laminations containing flattened cell nuclei Dystrophic …

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Odontogenic cysts-III

The epithelial lining has characteristic odontogenic features with a prominent basal layer consisting of palisaded columnar or cuboidal cells and hyperchromatic nuclei which are polarized away from the basement membrane   A few ghost cells may contain nuclear remnants but these are in various stages of degeneration and in the …

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Odontogenic cysts-II

The term odontogenic keratocyst was 1st used by Philipsen in 1965. The name ‘primordial cyst’ has been used synonymously with OKC for years. The cyst with following  characteristics are called as OKCs. Corrugated para/orthokeratinized surface. Uniform thickness of epithelium  6-10 layers thick. Prominent palisaded, polarized basal layer often described as …

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Odontogenic cysts-I

Developmental Dentigerous cyst Eruption cyst Odontogenic keratocyst Gingival cyst of newborn Gingival cyst of adult Lateral periodontal cyst Calcifying odontogenic cyst Glandular odontogenic cyst B. Inflammatory Periapical cyst Residual cyst Paradental cyst   Derived from rests of Malassez Periapical cyst Residual cyst Derived from reduced enamel epithelium Dentigerous cyst Eruption …

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Odontgenic Tumors-VII

At  the end of the lecture student should be able to Describe etiology, Enlist clinical features, Enlist radiological features, Enlist Histopathological features of Metastasizing ameloblastoma, Ameloblastic carcinoma, Primary intraosseous carcinoma, Ghost cell odontogenic carcinoma, Clear cell odontogenic carcinoma,& Ameloblastic fibrosarcoma   Etiology, Clinical features, Radiological features,& Histopathological features of Metastasizing …

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objective lens seminar

On modern microscopes, up to six objectives are mounted onto a revolving nosepiece to enable rapid change from one to another and ideally, the focus and field location should      require the minimum of adjustment. SPRING LOADED   OBJECTIVES-    Many objectives designed with close working distances have a spring-loaded retraction stopper …

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normalradiographicanatomy

At the end of the presentation the learner should be able to Describe anatomy of tooth Describe  supporting structures of tooth Describe normal radiographic anatomical landmarks of maxilla Describe normal radiographic anatomical landmarks of mandible ANATOMIC LANDMARKS OF MAXILLA Intermaxillary suture Anterior nasal spine Nasal fossa and Nasal septum Incisive …

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Non-Odontogenic cysts-VI

Median palatal cyst Median mandibular cyst Epidermoid cyst Dermoid cyst Thyroglossal duct cyst Branchial cleft cyst (cervical lymphoepithelial cyst) Oral lymphoepithelial cyst   Incisive Canal Cyst Stafne Bone Cyst Traumatic Bone Cyst Surgical Ciliated Cyst (of Maxilla) Nasolabial cyst Median palatal cyst Median mandibular cyst Epidermoid cyst Dermoid cyst Thyroglossal …

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Non neoplastic diseases 1

The mucinous material is basophilic or acidophillic and contains  neutrophils and large oval foam cells the histocytes . The base of the mucocele will reveal feeder duct. Long standing mucoceles will show acinar degeneration with fibrosis and minimal inflammation.   Term is used for mucoceles that occur in the floor …

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non neoplastic disease 6

Text book of oral pathology Shafer’s, 5 & 6th edition Surgical Pathology of Salivary Glands  Ellis 1st  Edition Color Atlas of Oral Diseases Cawson, R.  2nd edition Oral  and Maxillofacial Pathology Neville, Brad W.  2nd Lucas’s Pathology Of Tumor’s of the Oral Tissues Cawson, R. A., Bennie, W. H 5th …

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my langerhan cell ppt

In 1868 PAUL LANGERHANS, a medical student interested in the anatomy of skin nerves, described a dendritically shaped cell population located in squamous epithelia of the epidermis, in the suprabasal layers, by using a gold chloride impregnation technique. Epidermis has two types of dendritic cells: Langerhans cells: These cells are …

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Multilocular radiolucencies

When whole canal is increased- serpiginous shape Vessel –phleboliths; Vessel wall calcification – tram line Teeth displacement Mand & mental foramen enlarged Involved bone enlarged Developing teeth larger , erupt earlier   Odontogenic tumor Arises from- odontogenic epi or odontogenic cyst Types solid, unicystic, or multicystic Pericoronal / not necessarily …

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MRI & CT Basics.

A radio frequency pulse that has the same frequency as the precising protons , can cause resonance , ie transfer energy to protons . This results in more protons being anti parallel leading to decrease in longitudinal magnetization. The RF pulse results in a new magnetic vector , the transversal …

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MOUNTING 1

For histological examination the specimen has to undergo a complex processing. This may involve cutting it into very thin sections with a microtome, fixing it to prevent decay, dehydrating , staining it, and impregnating or infiltrating it with some transparent solid substance. As a result of this process the specimen usually ends up firmly attached to the …

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