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orofacial pain-part-II

  • Neurotransmitters are divided into 2 types-
  • Small rapid acting molecules –Acetylcholine,
  •                                        Norepinephrine, Glutamate, Aspartate,
  •                                        Serotonin(excitatory)
  •                                      – GABA, Glycine, dopamine(Inhibitory)
  • Larger slower acting molecules-
  •       Substance P, Endorphins


  • Acetylcholine is a very widely distributed excitatory neurotransmitter that triggers muscle contraction and stimulates the excretion of certain hormones. In the central nervous system, it is involved in wakefulness, attentiveness, anger, aggression, sexuality, and thirst, among other things.
  • Alzheimer’s disease is associated with a lack of acetylcholine in certain regions of the brain

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