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Root Canal Irrigants

  • First used by Semmelweis (1847) as a hand disinfectant.
  • Dakin used 0.5% hypochlorite solution for irrigating the wounds of soldiers during world war I. (Dakin’s solution)
  • Crane advocated the use of Dakin’s solution in endodontic therapy mainly due to its antibacterial, lubricative and tissue dissolving property.
  • Hypochlorite incident occurs due to accidental (forceful) injection of the solution beyond the root apex.
  • Clinical features include severe pain, rapidly developing edema, hematomas, necrosis and abscess.
  •   The complications are caused by oxidizing effects of NaOCl on the vital tissues surrounding the endodontically treated tooth followed by an inflammatory reaction of the body.

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